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New Peptide Serum Complements In-Office Aesthetic Treatments

01/08/2026
ZO

ZO® Skin Health has introduced the Peptide Facial Refining Concentrate, an advanced at-home serum formulated to complement professional aesthetic procedures and enhance overall facial rejuvenation. The launch adds to the company’s physician-dispensed portfolio with a high-performance topical designed to visibly refine facial contours, restore volume, and smooth fine lines.

The serum is powered by 4 proprietary peptide technologies and ZO’s exclusive ZPOLY™ Complex, which is intended to support the skin’s barrier and reduce visible redness. According to the brand, the formula improves elasticity and facial geometry in just 12 weeks, whether used as a standalone or in tandem with in-office treatments.

Clinical results from an independent 12-week study (n=49; ages 47–72; Fitzpatrick I–VI), conducted with the addition of Gentle Cleanser and Sheer Fluid Broad-Spectrum Sunscreen SPF 50, reported:

  • 92% saw a reduction in fine lines

  • 86% saw visible improvement in facial hollow areas

  • 84% noted more youthful facial geometry

ZO® Skin Health positions the serum as a bridge between professional procedures and daily skincare, offering a patient-friendly way to maintain and extend in-office results.

"Peptide Facial Refining Concentrate is designed to optimize outcomes and support long-term skin health, especially for patients undergoing advanced facial rejuvenation," the company stated. The $265 formulation is now available through authorized ZO® Skin Health providers.

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