Lumenis Debuts Stellar M22™ with XPL™ at ASDS 2025, Showcases Single-Session Clearance Data

Lumenis Be. Ltd. introduced the next-generation Stellar M22™ with XPL™ Technology during the 2025 Annual American Society for Dermatologic Surgery (ASDS) Meeting, highlighting single-session clearance rates of up to 100% for vascular and pigmented lesions. The multi-application aesthetic platform integrates four advanced modalities and is approved to treat more than 30 indications.

According to the company, the latest system features XPL™ (Expert Pulsed Light) technology with 8 expert filters, sub-pulsing functionality, and a proprietary Advanced Pulse Design for precise control of treatment parameters. New enhancements include XPL Glide Mode for faster, in-motion treatments and ResurFX® BrushFX™ Mode, designed to deliver refined texture blending.

“The Stellar M22™, backed by 30 years of refinement, delivers consistently outstanding clinical results,” said Gilly Munavalli, MD, MHS, FAAD, Director and Founder of Dermatology, Laser, & Vein Specialists in Charlotte, North Carolina. “Having used an M22 for the past 15 years with great results, I am amazed at how much the Stellar surpasses its predecessor in every way. Enhanced by Expert Pulsed Light technology, its advanced pulse design and practitioner focused usability make it an indispensable tool in my practice. The new XPL Glide mode further expands its capabilities with the ability to perform treatments more quickly, comfortably, and with minimal downtime.”

In retrospective data presented at ASDS 2025, more than 75% of cutaneous lesions showed excellent clearance after a single XPL session, and more than half showed good clearance after 1 pass. Lumenis noted that the platform is suitable for all skin types and enables hybrid treatments, including PhotoFABULOUS™ and SmoothGlo™.

“At Lumenis, innovation is at the heart of everything we do, and the new Stellar M22 with XPL™ Technology is a shining example of that commitment,” said Tzipi Ozer-Armon, CEO of Lumenis. “This powerful, multi-application platform meets the evolving needs of today's aesthetic providers, offering unparalleled versatility and clinically proven efficacy across a wide range of skin concerns. With Stellar M22, we are not just delivering a platform—we are providing a transformative tool that elevates clinical practice and empowers patients to look and feel their best.”