LevEllis Launches Regenerative Serum Featuring Skin-Specific Secretome Technology

LevEllis, Inc. announced the launch of PROVOQUE™, a physician-dispensed regenerative skincare serum formulated with a proprietary skin-specific secretome. Developed by surgeon and molecular biologist Laura Ellis, MD, the product represents a new approach in medical-grade skincare by delivering a complete matrix of biologically active factors derived from human skin progenitor cells.

"We are thrilled to introduce a next-generation advancement in regenerative aesthetics—one that offers new potential for both skin and hair revitalization" Dr. Ellis said. "As regenerative medicine reshapes the future of aesthetics, PROVOQUE^™ stands at the intersection of scientific evidence, innovation, and elegance."

Unlike products that isolate select growth factors or exosomes, PROVOQUE™ contains a full complement of peptides, cytokines, microRNA, exosomes, and regenerative molecules—components designed to mimic the native skin environment. The formulation aims to support tissue repair, reduce inflammation, and promote skin rejuvenation, according to a press release.

PROVOQUE™ is formulated without fragrances, oils, or solvents, and is designed to preserve the biological integrity of its active components while minimizing potential for irritation or inflammatory response.

"What truly distinguishes PROVOQUE^™ is that it is built upon skin-specific cellular science. These young, bioengineered skin progenitor cells produce the complete skin secretome—a robust, biologically active blend of naturally occurring growth factors, exosomes, and the glycoprotein Fetuin-A," said Hans Keirstead, PhD, inventor of the PROVOQUE^™ technology and internationally recognized stem cell expert. "A dermatology-assessed, peer-reviewed study published in Journal of Drugs in Dermatology shows it reveals healthier, smoother-looking skin from the inside out in as early as 14 days."

LevEllis is supported by a scientific advisory board of Julie Woodward, MD; Jordan R. Plews, PhD; and Gabriel Nistor, MD.