The RHA (Resilient Hyaluronic Acid) Collection of dermal fillers hits the market from Revance this fall. The RHA dermal fillers are designed with a crosslinking method that preserves the hyaluronic acid network in efforts to more closely mimic natural HA found in the skin. Results of an 18-month, head-to-head, randomized, controlled study published in Dermatologic Surgery, found high levels of improved satisfaction immediately after injection and in the long-term for both investigators and participating subjects for RHA 2, 3, and 4. Three-dimensional (3D) skin topography measurements showed better long-term improvement of nasolabial fold volume with gels in the RHA Collection.

The RHA line has been available outside the US for some time, and we have gained a substantial amount of experience with these products. Here are five things to know.

1. The RHA line is made up of four distinct gels. Three of these have been approved in the US. RHA1 is still in the pipeline in the US and is used for the treatment of fine lines and treatment of the tear trough.

2. RHA4 is a unique gel that may be injected in both the deep and superficial fat compartments to achieve lift and volume. The product is easily integrated into the tissue and does not have a boggy effect when volumizing the mid face, even when placed superficially. This is due to its pliability and stretching properties.

3. Both RHA2 and RHA3 may be used for the injection of the lips. RHA2 is mainly used for older patients to achieve a natural result and in the younger population group who have never had their lips injected in the past and want to try that out. RHA3 is the main filler for natural volumizing of the lips.

4. The RHA line has been formulated to cater mainly to the animated face. There is a respect that static lines change where fillers are injected and the face is in motion; current materials do not have the properties that take that into consideration.

5. When compared to other fillers that are FDA approved, the RHA line will provide a much needed gradient that will fill a particular niche. That would be that natural results should be seen not just in still pictures, but when showing emotion.