In each edition, Modern Aesthetics® asks top cosmetic physicians what new cosmeceuticals they are offering to patients today. In this issue, Edwin F. Williams III, MD, a facial plastic surgeon with offices in Albany, NY & St Thomas, USVI, shares his experience with Defenage's Clinical Power Trio which he has been offering since July 2017.

What is the DefenageClinical Power Trio?

The Defenage Clinical Power Trio is a collection of three products that utilize the power of defensins to regenerate skin. The trio includes full sizes of the 2-Minute Reveal Masque, 24/7 Barrier Balance Cream, and 8-in-1 Bioserum Emulsion. Using these products together visibly improves up to 16 signs of aging in six weeks.

Defensins are proteins that communicate with very specific stem cells in the dermis. These stem cells help reproduce young healthy skin cells. As the old cells are exfoliated off, these young cells migrate up to the surface of the skin, resulting in a clear, smooth, and glowing appearance.

How do the three products work synergistically?

The regimen starts with the 2-Minute Reveal Masque, which removes dull, unwanted skin cells with ultrafine sugar crystals and Triple Enzyme technology. This step amplifies results by preparing the skin to receive active nutrients from the cream and serum that follow. The masque can be used once or twice per week for optimal results.

Next, patients apply the 24/7 Barrier Balance Cream. This cream replenishes and balances the skin's natural barrier function. It is also loaded with defensins, antioxidants, and brighteners. The application of the cream under the serum helps the serum to more easily affect the skin. It is used twice daily on clean skin.

After the cream, patients apply the 8-in-1 Bioserum Emulsion. This “smart” formula provides the benefits of eight serums in one and an unprecedented concentration of defensins. With twice daily use, skin becomes brighter, wrinkles smooth out, pores appear smaller, redness is reduced and firmness restored. It is ideal around the eye area. I tell patients to follow the Defenage regimen with broad spectrum SPF 30+ and makeup as desired during the day.

are your patients Happy with the results seen with Defenage?

The benefits of the product include improvement to tone and texture of skin, added moisture, and an optimal bio-environment for skin regeneration. Our patients feel that there is a noticeable difference to the skin within four to six weeks of consistent use, including smaller pore size.

How do you incorporate physician-based skin care in practice?

We do an individual skin analysis with all of our patients to best determine their needs. We suggest Defanage to most of our patients who have aging skin or specific needs that will be addressed with this line. We also intergrate Defanage with microneedling treatments. Our patients feel that they have a quicker recovery time when using these products post-procedure. We hear from our patients and staff how much they love this new addition to our skincare line.