In each issue, Modern Aesthetics® magazine asks top cosmetic dermatologists about the newest cosmeceuticals that they are offering to patients. Here, Jeanine B. Downie, MD, FAAD, director of image Dermatology PC in Montclair, NJ, gives us a sneak peek of TNS Advanced+ Serum from SkinMedica, which is slated to launch in mid-June*.

What is TNS Advanced+ Serum?

Jeanine B. Downie, MD: TNS Advanced+ Serum is a next-generation serum from SkinMedica. TNS Advanced+ Serum uses multipotent resignaling complex growth factor technology to create a next generation growth factor blend. The growth factor blend is paired with peptides, botanicals, and marine extracts that were strategically selected to support the efficacy of the growth factor blend, leading to dramatic visible results. Of note, this formulation is colorless and odorless.

How well does it work?

Dr. Downie: In a 24-week clinical study, TNS Advanced+ Serum reduced the appearance of global fine lines and wrinkles, improved the appearance of skin roughness and overall hyperpigmentation/photodamage, and helped to reduce the appearance of sagging of the skin. Additionally, TNS Advanced+ Serum can provide “prejuvenation” by supporting growth factor levels before they decline, helping to maintain collagen and elastin levels in the skin.

How do you suggest that your patients use this product?

Dr. Downie: I recommend my patients use it twice a day. In the clinical study, statistically significant results were measured as early as two weeks, with progressive improvements over 24 weeks. Using Face-Q, a third-party validated measurement of patient-reported outcomes, subjects felt they looked an average of six years younger after 12 weeks of use.

How does TNS Advanced+ Serum stand apart from other serums on the market?

Dr. Downie: TNS Advanced+ Serum stands out because it tackles the visible signs of aging by targeting the source of aging skin and addressing declining growth factor levels.

What products or procedures does TNS Advanced+ Serum complement?

Dr. Downie: As part of the DiamondGlow experience, we recommend following the treatment with TNS Advanced+, HA5 Rejuvenating Hydrator, and Essential Defense Sunscreen from SkInMedica. DiamondGlow is a skin-resurfacing treatment that combines exfoliation, extraction, and infusion of condition-specific serums.

*Dr. Downie disclosed that she is a paid Allergan consultant.